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This is a consequence when the adrenal glands are overly stimulated to produce the prohormone dehydroepiandrosterone or DHEA. By the 1950s, competitive weight lifters were taking them to build muscle mass and gain weight quickly, and professional athletes in a variety of sports have been using them ever since. The slow pace of clinical development of these agents as anabolic therapies illustrates the regulatory and conceptual barriers that have hindered this field. Initially, the use of steroids was limited to "bodybuilders" and professional athletes, but the practice has now carried over into a widespread segment of society, including young athletes who aspire to someday become professionals.



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